Table 3.
Panther classification of Biological processes, Molecular functions and Pathways significantly enriched in the set of 37 genes
| Observed Genes • | Expected Genes •• | p-value ••• | |
|---|---|---|---|
| BIOLOGICAL PROCESS | |||
| Cellular process | |||
| Establishment or maintenance of chromatin architecture | 4 | 0.55 | 2.12E-03 |
| Cellular component organization | |||
| Organelle organization | 4 | 0.59 | 2.85E-03 |
| Transport | |||
| Intracellular protein transport | 9 | 2.98 | 2.16E-03 |
| Vesicle-mediated transport | 7 | 2.10 | 4.26E-03 |
| Endocytosis | 4 | 1.04 | 1.96E-02 |
| System process | |||
| Neurotransmitter secretion | 3 | 0.63 | 2.45E-02 |
| MOLECULAR FUNCTION | |||
| Catalytic activity | |||
| GTPase activity | 3 | 0.52 | 1.53E-02 |
| Enzyme regulator activity | |||
| Peptidase inhibitor activity | 2 | 0.32 | 4.08E-02 |
| Binding | |||
| Chromatin binding | 2 | 0.34 | 4.59E-02 |
| PATHWAYS | |||
| Ubiquitin proteasome pathway | 2 | 0.13 | 7.19E-03 |
• Number of genes, in the dataset of 37, that map to the indicated Panther classification categories
•• Expected number of genes, in the dataset of 37, based on the NCBI reference list of human genome
••• p-value as determined by the binomial statistic. A cutoff of 0.05 has been applied