Table 2.
Response to ovarian stimulation and clinical outcomes
| Group A (397 cycles) | Group B (81 cycles) | Group C (73 cycles) | P-value | |
|---|---|---|---|---|
| E2 level, hCG day (pg/mL)a | 1930.2 ± 1319.1 | 1725.3 ± 1314.0 | 2017.0 ± 1306.7 | NS |
| Endometrial thickness, hCG day (cm)a | 1.1 ± 0.2 | 1.1 ± 0.2 | 0.9 ± 0.2b | 0.001 |
| No. of oocytes retrieveda | 11.4 ± 7.2 | 11.8 ± 8.2 | 10.2 ± 5.0 | NS |
| No. of fertilized oocytesa | 8.2 ± 5.6 | 8.3 ± 6.4 | 7.5 ± 3.9 | NS |
| Fertilization rate per retrieved oocyte (%)a | 82.2 ± 18.7 | 81.7 ± 17.0 | 82.1 ± 19.6 | NS |
| No. of embryos transferreda | 3.1 ± 0.8 | 3.2 ± 0.8 | 3.1 ± 0.8 | NS |
| Implantation rate (%) | 264/1158 (22.8) | 55/251 (21.9) | 28/228 (12.3)b | 0.002 |
| 2000–2004 (290 cycles) | 133/627 (21.2) | 25/123 (20.3) | 11/102 (10.8)b | 0.04 |
| 2005–2009 (261 cycles) | 131/531 (24.7) | 30/128 (23.4) | 17/126 (13.5)b | 0.03 |
| Clinical pregnancy/cycle (%) | 224/397 (56.4) | 43/81 (53.1) | 23/73 (31.5)b | 0.02 |
| 2000–2004 (290 cycles) | 122/219 (55.7) | 24/43 (55.8) | 8/28 (28.6)b | 0.02 |
| 2005–2009 (261 cycles) | 102/178 (57.3) | 19/38 (50.0) | 15/45 (33.3)b | 0.02 |
| Abortion/clinical pregnancy (%) | 29/224 (12.9) | 9/43 (20.9) | 12/23 (52.2)b | <0.001 |
| 2000–2004 (290 cycles) | 16/122 (13.1) | 5/24 (20.8) | 5/10 (50.0)b | 0.009 |
| 2005–2009 (261 cycles) | 13/102 (12.7) | 4/19 (21.1) | 7/13 (53.8)b | 0.001 |
| Ectopic pregnancy/clinical pregnancy (%) | 9/224 (4.0) | 1/43 (2.3) | 0/23 (0.0) | NS |
| 2000–2004 (290 cycles) | 5/122 (4.1) | 1/24 (4.2) | 0/10 (0.0) | NS |
| 2005–2009 (261 cycles) | 4/102 (3.9) | 0/19 (0.0) | 0/13 (0.0) | NS |
| Live birth/cycle (%) | 186/397 (46.9) | 33/81 (40.7) | 11/73 (15.1)b | <0.001 |
| 2000–2004 (290 cycles) | 101/219 (46.1) | 18/43 (41.9) | 5/28 (17.9)b | 0.017 |
| 2005–2009 (261 cycles) | 85/178 (47.8) | 15/38 (39.5) | 6/45 (13.3)b | <0.001 |
NS not significant.
aData are mean ± SD.
bSignificantly different to corresponding values in group A and B (P < 0.05).