. Author manuscript; available in PMC: 2012 Dec 1.

Published in final edited form as: Mol Genet Metab. 2011 Aug 7;104(4):661–665. doi: 10.1016/j.ymgme.2011.08.001

Table 2. Association of SIRT1 tag SNPs with BMI in the population-based sample of 3501 Pima Indians.

SNP	M/m	Sex	mAF	BMI^a			P^b	P^c

				M/M	M/m	m/m
rs7895833	A/G	All	0.48	37.3 ± 8.4	37.2 ± 8.5	37.0 ± 8.2	0.92	0.90
		Male		35.9 ± 8.1	35.1 ± 7.8	35.7 ± 7.8
		Female		38.3 ± 8.5	38.5 ± 8.7	38.0 ± 8.4
rs10509291	T/A	All	0.14	36.9 ± 8.2	37.2 ± 8.5	37.9 ± 9.8	0.52	0.49
		Males		35.3 ± 7.7	35.2 ± 8.2	36.2 ± 7.8
		Females		38.0 ± 8.4	38.6 ± 8.5	39.5 ± 11.3
rs7896005	A/G	All	0.30	37.0 ± 8.5	37.2 ± 8.5	37.2 ± 8.2	0.45	0.60
		Male		35.4 ± 8.0	35.1 ± 7.6	35.9 ± 8.8
		Female		38.1 ± 8.5	38.6 ± 8.7	38.3 ± 7.5
rs4746720	T/C	All	0.33	37.4 ± 8.6	37.0 ± 8.5	36.7 ± 7.6	0.67	0.27
		Male		35.3 ± 8.0	35.3 ± 8.1	35.3 ± 7.5
		Female		38.8 ± 8.7	38.2 ± 8.6	37.7 ± 7.6

Unadjusted mean BMI ± SD by genotypic group is shown.

Additive P-values were adjusted for age, sex, birth year and family membership in the entire sample, and age, birth year and family membership in males and females alone.

P-values for sex interaction.