Figure 3.
Effect of emulsions on antibody response induced by immunization with recombinant malaria antigen. BALB/c mice were immunized twice with PbCSP antigen formulated with emulsions containing squalene, grapeseed, or sesame oil. Antigen-specific IgG were determined by ELISA. The antibody responses from the grapeseed and sesame oil groups were below the limit of detection. In the antigen alone group, only one mouse showed a response above the lower limit of detection. n = 5 per group, and data are shown as mean and s.e.