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. Author manuscript; available in PMC: 2012 Nov 28.
Published in final edited form as: Vaccine. 2011 Sep 9;29(51):9563–9572. doi: 10.1016/j.vaccine.2011.08.089

Table 2.

Emulsion physicochemical and biocompatibility characterization

oil Particle Size
(nm, T=0)
Polydispersity Particle Size
(nm, T=6mo)
Polydispersity Dynamic
Viscosity
(cP, T=0)
Dynamic
Viscosity
(cP, T=6mo)
Zeta
Potential
(mV, T=0)
Zeta
Potential
(mV, T=6mo)
Hemolysis %
(T=0)
squalene 119 0.18 134 0.21 1.6 NM −27.5 −28.1 0.2%
grapeseed 119 0.08 121 0.10 1.6 1.6 −21.4 −15.8 0.7%
sesame 107 0.09 109 0.12 1.5 1.5 −25.7 −20.4 0.4%
soybean 91.7* 0.09* 98.6 0.17 1.5 1.6 −19.7 −28.1 0.3%
Miglyol 810 119 0.15 129 0.21 1.6 1.6 −20.2 −24.4 0.3%
Fluorinert FC-40 119 0.30 NM NM 1.6 1.6 −5.8 −19.6 0.2%

Notes and abbreviations: T=0 refers to at or near the day of manufacture; T=6mo refers to ~6 months post-manufacture at 5°C storage temperature; NM, not measured due to insufficient sample volume or measurement quality failure. Size measurement is the z-avg, which represents the intensity-biased average size value from dynamic light scattering.

*

Measured using the Malvern Zetasizer Nano instead of the Malvern Zetasizer APS.