Table 2.
Functional annotation clustering with all genes present in three copies on Mmu17
| Cluster | Enrichment scorea | GO term | Genes |
|---|---|---|---|
| 1 | 0.91 | Protein localization | SFT2D1, SNX9, FGFR1OP, SYTL3 |
| Protein transport | SFT2D1, SNX9, SYTL3 | ||
| 2 | 0.70 | Membrane; insoluble; cell fraction | SNX9, TIAM2, SYTL3 |
| 3 | 0.66 | Microtubule cytoskeleton; cytoskeletal part | EZR, RPS6KA2, FGFR1OP, DYNLT1E, DYNLT1C, DYNLT1B |
| Intracellular and nonmembrane-bounded organelle | EZR, RPS6KA2, FGFR1OP, DYNLT1E, DYNLT1C, DYNLT1B | ||
| 4 | 0.41 | Nucleoside binding | NOX3, RPS6KA2, TCP10A, PDE10A, TCP10B, TTLL2 |
| Nucleotide binding | NOX3, RPS6KA2, TCP10A, PDE10A, TCP10B, RBM16, TTLL2 | ||
| Ribonucleotide binding | RPS6KA2, TCP10A, PDE10A, TCP10B, TTLL2 | ||
| ATP binding | RPS6KA2, TCP10A, TCP10B, TTLL2 | ||
| Transition metal ion binding | NOX3, ZDHHC14, PDE10A, SYTL3 | ||
| Zinc ion binding | ZDHHC14, PDE10A, SYTL3 | ||
| Metal ion binding | NOX3, ZDHHC14, RPS6KA2, PDE10A, SYTL3 |
aThe Group Enrichment Score, the geometric mean (in-log scale) of members’ P values in a corresponding annotation cluster, is used to rank their biological significance