Table III.
Comparison of pAx Values Obtained on the Guinea-Pig Ileum and the Air-Perfused Lung
The total number of individual determinations is given in parentheses with the standard deviation. The results on the ileum are from Schild (1947a)
| pA2 | pA10 | ||||
|---|---|---|---|---|---|
| Active Drug | Antagonist | Ileum 14 min. | Air-perfused Lung 30 min. | Ileum 14 min. | Air-perfused Lung 30 min. |
| Histamine | Mepyramine | 9.46 (5, 0.22) | 9.37 (3, 0.16) | 8.36 (1) | 8.38 (3, 0.28) |
| Diphenhydramine | 8.02 (9, 0.28) | 7.80 (4, 0.22) | 7.02 (4, 0.31) | 6.92 (3, 0.74) | |
| Pethidine | 6.13 (5, 0.46) | 6.15 (2, 0.08) | 5.00 (5, 0.21) | 5.06 (4, 0.23) | |
| Atropine | 5.64 (3.018) | 5.91 (4, 0.61) | 4.60 (3, 0.24) | 5.03 (3, 0.68) | |
| Acetylcholine | Atropine | 8.61 (11, 0.15) | 8.76 (2, 0.63) | 8.05 (3, 0.13) | 7.63 (6, 0.64) |