Table 1.
Effects of ATP on segments of gastrointestinal tract
| Animal | Gut segment | ATP (g/ml) | Response |
|---|---|---|---|
| Guinea-pig | stomach | 10−5–10−4 | — |
| ileum | 10−6–10−4 | —(low conc.)+(high conc.) | |
| colon | 5 × 10−6–2 × 10−5 | — | |
| Rabbit | stomach | 10−5-10−4 | —(low conc.)+(high conc.) |
| ileum | 10−6-10−4 | — | |
| colon | 10−5-10−4 | — | |
| Rat | stomach | 2 × 10−6–2 × 10−5 | — followed by + |
| duodenum | 2 × 10−6–10−5 | — | |
| colon | 2 × 10−5 | — | |
| Mouse | ileum | 5 × 10−6–2 × 10−5 | — |
| colon | 5 × 10−6–5 × 10−5 | —(low conc.)+(high conc.) | |
| Toad | stomach | 5 × 10−7–5 × 10−4 | —, +, or + followed by − |
+ = contraction during application of ATP.
− = relaxation or inhibition of spontaneous movements.