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. 2011 Sep 29;5:153. doi: 10.1186/1752-0509-5-153

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Copyright ©2011 Pérez et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cell-to-cell heterogeneity at fixed average activation. Cell fluorescence brightness distributions measured for experiments #2 and #3 in Figure 4B. (A)-(C) Distributions collected for two-HSL combinations that generated ~25% of full lux activation (Experiment #2) and (D)-(F) distributions collected for combinations that generated ~60% of full lux activation (Experiment #3). The dashed curves show maximum likelihood fits to a gamma distribution. Each histogram is derived from roughly 200 individual cells.