Fig.1.
Treatment with 2-ME significantly inhibited the proliferation of SK-N-SH and SH-SY5Y cells. SK-N-SH (A) and SH-SY5Y (B) cells were treated with 2-ME at indicated concentrations for 48 or 72 h. Cell viability was tested by SRB assay as described in the Methods. (C) SK-N-SH cells were treated with 5 μM 2-ME for 1–8 days. Cell viability was detected by Trypan blue exclusion assay. The data are expressed as inhibition rate and represent the mean ± SEM of three separate experiments. *P < 0.05 vs. control.