Table 2.
Percent yields and cytotoxic activities.
Sample | Part used | Percent yield | IC50 (μg/ml) ± standard deviation (SD) | SIc | |
---|---|---|---|---|---|
HepG2 | Vero | ||||
Melphalana | 37.7 ± 9.8 | 59.9 ± 3.2 | 1.6 | ||
Glochidion daltonii | Woody stem and twig |
4.3 | 109.1 ± 8.8 | 38.7 ± 10.0 | 0.7 |
Cladogynos orientalis | Leaves | 7.4 | 402.0 ± 4.3 | 205.4 ± 5.6 | 0.5 |
Catimbium speciosum | Rhizomes | 2.6 | 55.7 ± 8.1 | 19.7 ± 2.5 | 0.4 |
Acorus tatarinowii | Underground stem (rhizomes), |
10.5 | 364.8 ± 6.6 | 182.5 ± 2.1 | 0.5 |
Amommum villosum | Pseudostem and leaves |
7.21 | 119.2 ± 8.6 | Inactiveb | > 4.2 |
Pinus kesiya | Woody twig | 2.2 | 52.0 ± 5.8 | Inactiveb | 9.6 |
Percent yields of the crude extracts from six indigenous plants and their cytotoxic activities after 24-hour treatment in human hepatocarcinoma (HepG2) and normal African green monkey kidney epithelial (Vero) cell lines.
Data are expressed as the means of triplication.
a Standard anticancer drug and positive control.
b IC50 > 500 μg/ml is considered to be inactive.
c SI refers to Selectivity Index, SI value > 3 indicating high selectivity [9].