Table 4.

Exercise capacity and age, dyspnea, and obstruction index among 260 Dutch and 151 Swiss chronic obstructive pulmonary disease patients (total cohort N = 411) enrolled in the International Collaborative Effort on Chronic Obstructive Lung Disease: Exacerbation Risk Index Cohorts prospective cohort study

		Dutch cohort	Swiss cohort	Total cohort
Sit-to-stand test (x/minute)	p5, p50, p95	0, 14, 24	11, 22, 40	0, 17, 35
GOLD II		0, 15, 25	12, 23, 40	0, 18, 35
GOLD III		0, 15, 23	0, 20, 42	0, 17, 39
GOLD IV		0, 10, 17	13, 18, 30	0, 13, 26
Hand grip test
Right hand (kg)	p5, p50, p95	16, 30, 52	20, 40, 58	18, 32, 56
GOLD II		15, 30, 54	18, 40, 58	17, 32, 56
GOLD III		18, 32, 49	21, 40, 66	18, 34, 56
GOLD IV		16, 30, 50	20, 41, 54	16, 36, 53
Left hand (kg)	p5, p50, p95	12, 28, 50	20, 36, 54	14, 32, 52
GOLD II		12, 28, 50	20, 36, 56	14, 32, 52
GOLD III		14, 30, 50	18, 35, 54	16, 32, 53
GOLD IV		14, 27, 48	16, 37, 50	14, 29, 50
ADO index	p5, p50, p95	1, 5, 8	1, 3, 6	1, 4, 7
DOSE index	p5, p50, p95	0, 2, 6	0, 1, 4	0, 1, 5

Notes: ADO index is an estimation of 3-year risk of mortality. A score of five indicates a 3-year risk of mortality of 16.3%, score of 3 indicates a 3-year risk of mortality of 11.5%, and score of four indicates a 3-year risk of mortality of 13.7%. DOSE index is an estimation of health status as measured by the CCQ total score. Numbers in GOLD stage II, III, and IV are 174, 64, and 22 for Dutch, 95, 40, and 16 for Swiss, and 269, 104, and 38 for total cohort.

Abbreviations: ADO, age, dyspnea and obstruction; DOSE, dyspnea, obstruction, smoking status, and exacerbation frequency; GOLD, Global Initiative for Chronic Obstructive Lung Disease; p5, fifth percentile; p50, median; p95, 95th percentile.