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. 2009 Dec 2;10:124. doi: 10.1186/1471-2350-10-124

Table 1.

Allele and Genotype frequencies for CYP2C8, CYP2C9 and CYP2C19 alleles observed in the Ghanaian population (%, 95% CI in parenthesis)

CYP2C8*2 CYP2C9*11 CYP2C19*2
Total no. genotyped 203 195 169
Major allele homozygous 139 (68, 62.0 - 74.86) 190 (97.5, 95.22 - 99.66) 152 (90, 85.48 - 94.52)
Heterozygous 59 (29, 22.8 - 35.31) 4 (2, 0.06 - 4.04) 14 (8, 3.91, 12.09)
Minor allele homozygous 5 (3, 0.33 - 4.59) 1 (0.5, -0.49 - 1.51) 3 (2, -0.21, 3.77)
Major allele frequency 83 (79.35 - 86.65) 98 (96.61- 99.39) 94 (91.47- 96.53)
Minor allele frequency 17(13.35 - 20.65) 2 (0.61, 3.39) 6 (3.47, 8.53)

CI, Confidence Interval. CYP2C8*3, *4, CYP2C9*2, *3 *4, *5 and CYP2C19*3 variant alleles were not detected in this study