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. 2011 Nov 9;11:68. doi: 10.1186/1471-213X-11-68

Figure 7.

Figure 7

Dose Dependency of 5-HT's Effect on the Migration Velocity of FMB- or HB-NCCs. We measured and compared the "mean velocity" of both populations before (Vc) and after (Vd) the addition of 5-HT, and the graph shows the relationship between the Vd/Vc ratio (Rd/c) and each dose of 5-HT (*P < 0.05, **P < 0.01; error bars represent ± s.e.m.). The mean velocity of FMB-NCCs increased after the addition of 5-HT at 0.1 μM (cont: n = 201; 0.01 μM: n = 107, P = 0.798; 0.1 μM: n = 132, P = 0.000101; 1 μM: n = 100, P = 0.176; 10 μM: n = 82, P = 0.521) (A). No increase in the mean velocity of HB-NCCs was observed at any of the concentrations tested after the addition of 5-HT (B) (cont: n = 417; 0.01 μM: n = 214, P = 0.996; 0.1 μM: n = 187, P = 0.126; 1 μM: n = 194, P = 0.617; 10 μM: n = 207, P = 1.00).