Table 2.
Dosage of UTI prophylactic agents used in 1473 nursing home residents; Last columns: Norwegian guidelines on recommended UTI prophylactic treatments in nursing homes.
| Dosage of UTI prophylactic agents used in 1473 nursing home residents | Norwegian guidelines: recommended UTI prophylaxis in nursing homes | |||
|---|---|---|---|---|
| Agents used | Mean (SD) | Dosage range | Dosage | Comments |
| Methenamine | 1.87 g (0.47) | 1 - 2 g daily | 1 g twice daily | Low grade documentation**** |
| Vitamin C | 490 mg (370) | 60 - 2000 mg daily | - | Not recommended |
| Estrogens | - | 0.5 - 2 g daily* 0.5 - 1.5 mg weekly** |
- | Vaginal estrogens can be tried in recurrent UTIs |
| Cranberry | - | 1 - 2 capsules daily*** | - | Low grade documentation**** |
| Trimethoprim | 110 mg (26) | 100 - 160 mg daily | 100 mg daily | Consider local resistance pattern |
| Nitrofurantoin | 70 mg (35) | 50 - 150 mg daily | 50 mg daily | Less effective with low or intermediate eGFR*****, pulmonal and kidney function must be assessed if long term treatment |
* oral daily doses, ** vaginal weekly doses estriol (50 - 52 μg estradiol weekly), *** 2 residents received 4 ml mixture or 0.5 drinking glass of cranberry juice daily
**** Evidence grading system as commonly used in clinical practice Guidelines
***** Estimated glomerular filtration rate