Figure 5. Polymerization of 2 μM tau induced with varied ARA concentration (0 μM to 150 μM) measured by right-angle laser light scattering.
Wild-type (closed circles •) and 7-Phos tau isoform (open squares □) polymerization reactions with 2 μM protein (x-axis) and 0 to 75 μM arachidonic acid were measured by intensity of right-angle laser light scattering (y-axis) after 18 hours incubation at 25 °C. Individual graphs are shown for (A) 0N3R, (B) 1N3R, (C) 2N3R, (D) 0N4R, (E) 1N4R, and (F) 2N4R isoforms. Bars represent ± s.d. from 3 experiments.