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. 2011 Oct 28;17:2808–2817.

Table 7. Sensitivity, specificity, and positive and negative predictive values for the three LOXL1 SNPs.

SNP SE (95% CI) SP (95% CI) PPV (95% CI) NPV (95% CI)
rs1048661
Allele (T)
0.927 (0.889–0.965)
0.356 (0.285–0.427)
0.467 (0.393–0.541)
0.889 (0.843–0.935)
Genotype (TT)
0.889 (0.836–0.962)
0.562 (0.458–0.666)
0.556 (0.452–0.660)
0.901 (0.839–0.963)
rs3825942
Allele (G)
0.983 (0.964–1.002)
0.106 (0.061–0.151)
0.401 (0.329–0.473)
0.912 (0.870–0.954)
Genotype (GG)
0.966 (0.928–1.004)
0.199 (0.116–0.282)
0.424 (0.321–0.527)
0.906 (0.845–0.967)
rs2165241
Allele (C)
0.983 (0.964–1.000)
0.093 (0.050–0.136)
0.398 (0.326–0.470)
0.900 (0.000–0.944)
Genotype (CC) 0.978 (0.947–1.000) 0.164 (0.087–0.241) 0.416 (0.313–0.519) 0.923 (0.867–0.977)

SNP, single nucleotide polymorphism; SE, sensitivity; SP, specificity; PPV, positive predictive values; NPV, negative predictive values.