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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Circ Cardiovasc Imaging. 2011 Jul 5;4(5):506–513. doi: 10.1161/CIRCIMAGING.110.961649

Table 2. ROC Analysis of Echocardiographic Parameters for Identification of Severe MR.

Cutoff AUC (95% CI) Sensitivity, % Specify, % + LR −LR
3D VCA, cm2 0.41 0.96 (0.88–0.99) 97 82 5.50 0.04
2D ROA, cm2 0.32 0.95 (0.87–0.99) 94 85 6.40 0.07
VCW, cm 0.62 0.94 (0.86–0.98) 91 91 10.33 0.10
JA/LAA 0.39 0.78 (0.66–0.87) 65 88 5.50 0.40

ROC indicates receiver operating characteristic; MR, mitral regurgitation; AUC, area under the curve; CI, confidence interval; +LR, positive likelihood ratio; −LR, negative likelihood ratio; VCA, vena contracta area; ROA, regurgitant orifice area; VCW, vena contracta width; and JA/LAA, ratio of jet area to left atrial area.