Table 1.
Baseline characteristics. Median (range) or number of patients (%).
| AS+AQ | AS/AQ | |
|---|---|---|
| Artesunate PK group | N = 35 | N = 35 |
| Age (months) | 37 (7 – 59) | 32 (11 – 58) |
| Weight (kg) | 14 (7 – 17) | 12 (7.5 – 19) |
| Sex (n (%) males) | 25 (71) | 15 (43) |
| Temperature (°C) | 39.0 (37.5 – 40.6) | 38.7 (37.5 – 40.1) |
| Gametocytaemia (n (%) with gametocytes) |
6 (17) | 3 (9) |
| Hepatomegaly (n (%)) | 0 (0) | 1 (3) |
| Splenomegaly (n (%)) | 1 (3) | 1 (3) |
| Parasite count (/μL) | 30,000 (2000 – 162,000) | 29,000 (2000 – 393,000) |
| Amodiaquine PK group | N = 35 | N = 35 |
| Age (months) | 26 (12 – 59) | 29 (7 – 58) |
| Weight (kg) | 12 (7 – 31) | 12 (6 – 19) |
| Sex (n (%) males) | 16 (46) | 20 (57) |
| Temperature (°C) | 38.4 (37.5 – 40.2) | 38.4 (37.5 – 40.8) |
| Gametocytaemia (n (%) with gametocytes) |
1 (3) | 7 (20) |
| Hepatomegaly (n (%)) | 1 (3) | 0 (0) |
| Splenomegaly (n (%)) | 1 (3) | 2 (6) |
| Parasite count (/μL) | 29,600 (1000 – 170,000) | 27,000 (1000 – 468,000) |