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. Author manuscript; available in PMC: 2012 Nov 2.
Published in final edited form as: Adv Mater. 2011 Sep 26;23(41):4793–4797. doi: 10.1002/adma.201102948

Scheme 1.

Scheme 1

Synthesis route of NMP. a) 16 nm Mn-MNPs were coated with DMSA and dispersed in water. b) DMSA-coated Mn-MNPs were then treated with PVP and induced to form a nanoscale cluster. c) The clusters were encapsulated in silica by polymerizing TEOS via the Stöber process. A near infrared dye (VT680) was co-injected at this point to allow incorporation of the dye into the silica shell. d) The Stöber process was repeated to allow another layer of silica to form, protecting the dye from the external environment.