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. 2011 Nov 8;115(47):13925–13934. doi: 10.1021/jp207104w

Table 3. Differential Thermodynamic Profiles for Pairs of Dodecamer and Decamer Duplexes.

NaCla ΔΔHc ΔΔG°b,c Δ(TΔS)c ΔΔnNa+d ΔΔnwd
Substitution of dA6 with 7-Deaza-dA in DDD (DDD-1 Minus DDD)
10 40.0 2.3 37.7 0.9 19.0
100 35.5 5.1 30.4 0.7 15.0
Substitution of dA5 with 7-Deaza-dA in DD (DD-1 Minus DD)
10 23.7 1.8 21.9 0.7 13.0
100 18.2 2.5 15.7 0.4 8.0
a

Salt concentration in mM.

b

Determined at 20 °C.

c

kcal/mol.

d

Per mol DNA.