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. Author manuscript; available in PMC: 2012 Sep 27.
Published in final edited form as: ACS Nano. 2011 Aug 29;5(9):7235–7244. doi: 10.1021/nn202054f

Scheme 1.

Scheme 1

Synthesis of amine functionalized silica nanoparticles via a reverse microemulsion. Step 1 involves micelle formation. Step 2 is the addition of tetraethoxysilane (TEOS) to the emulsion to form monodisperse “seed” particles. Lastly, step 3 is the subsequent addition of TEOS and AHAP that co condense to form the AHAP/TEOS silica nanoparticles.