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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2011 Sep 15;50(11):1129–1139.e2. doi: 10.1016/j.jaac.2011.08.002

Figure 2.

Figure 2

Dopamine receptor D4 (DRD4)*Dose Effects on Parent- and Teacher-Rated Hyperactive-Impulsive Scores. Note: Participants with no copies of the 4-repeat (4R) allele experienced less reduction in symptoms as methylphenidate dose increased compared with 4R carriers. The 0 mg/kg/day dose corresponds to the placebo condition. OROS = osmotic-release oral system