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Putative mechanisms of combining condensing binding with active rDNA transcription. (A) Competition between condensin bunding and transcription. This scenarion is likely avoided in the wild-type rDNA, but is likely the only possible mechanism for rDNA segregation in the 20-repeat strain. (B) rDNA repeat specialization for rRNA production (active Pol I transcription) and nucleolar segregation (silent for Pol I transcription) in wild type budding yeast.
