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Transmission electron microscopic images of siRNA-loaded liposomes. (A) siRNA-loaded 1 mol% PEGylated liposomes. (B) siRNA-loaded 1 mol% PEGylated, RGD peptide-modified liposomes. The images were taken at 50,000× magnification from the suspended liposomal particles after negative staining. In the bottom-right corner, the local image was enlarged to view the interface of liposomes clearly. Bar = 0.2 μm.
Abbreviations: siRNA, small interfering RNA; PEG, polyethylene glycol.
