Table 1.
Characteristics | Noninvasive breast cancer |
Invasive breast cancer |
||||
---|---|---|---|---|---|---|
not tested for HER2, n | tested for HER2, n | p valuea | not tested for HER2, n | tested for HER2, n | p valuea | |
Total number | 525 | 13 | 579 | 2,475 | ||
Age at diagnosis, years | 0.03 | 0.4 | ||||
<45 | 47 | 4 | 56 | 250 | ||
45–59 | 218 | 2 | 229 | 971 | ||
60–69 | 157 | 5 | 143 | 679 | ||
≥70 | 103 | 2 | 151 | 575 | ||
Race/ethnicityb | 0.9 | 0.2 | ||||
White, non-Hispanic | 482 | 11 | 537 | 2,240 | ||
African American | 9 | 0 | 11 | 42 | ||
Hispanic | 5 | 0 | 10 | 38 | ||
Other | 12 | 0 | 8 | 77 | ||
Unknown | 17 | 2 | 13 | 78 | ||
ER statusc | <0.0001 | <0.0001 | ||||
Positive | 184 | 13 | 369 | 2,040 | ||
Negative | 30 | 0 | 106 | 410 | ||
Unknown | 311 | 0 | 104 | 25 | ||
Nodal involvementd | 0.007 | <0.0001 | ||||
Evaluated, negative | 100 | 7 | 358 | 1,511 | ||
Positive | 2 | 0 | 1,197 | 677 | ||
Not evaluated | 423 | 6 | 104 | 287 | ||
SEER stage | 0.02 | |||||
In situ | 525 | 13 | 0 | 0 | ||
Localized | 0 | 0 | 429 | 1,717 | ||
Regional | 0 | 0 | 127 | 679 | ||
Distant metastasis | 0 | 0 | 23 | 79 |
p values from Pearson's χ2 test with Yates' continuity correction.
The comparison is for white race versus all others.
The comparison is whether ER status is known or unknown.
The comparison is whether nodes were evaluated or not.