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. 2011 Oct 31;7:85. doi: 10.1186/1744-8069-7-85

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Copyright ©2011 Ohsawa et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of (+)-pentazocine [(+)PTZ] on the expression of ERK1 (A), ERK2 (C), phosphorylated ERK1 (B), and phosphorylated ERK2 (D) protein in the spinal cords of diabetic and non-diabetic mice. Spinal samples were collected 30 min after the i.t. administration of (+)PTZ. Immunoblots are from an experiment that is representative of 4 similar experiments. Each column represents the mean ± S.E.M of 4 separate experiments. *P < 0.05 vs. non-diabetic mice; #P < 0.05 vs. respective vehicle-treated group.