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. 2011 Nov 13;10:141. doi: 10.1186/1476-4598-10-141

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Copyright ©2011 Tahira et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Genomic loci encoding intronic lncRNAs are enriched in promoter-associated histone marks and start sites of capped transcripts. Distance distribution (X axis) of promoter-associated chromatin marks H3K4me3 binding sites (panels A, B), CpG islands (panels C, D) and CAGE Tags (panels E, F) relative to genomic coordinates of intronic (blue bars) and intergenic (green bars) transcripts expressed in pancreatic tissues (Y axis) were calculated. For comparison, distribution distances were calculated for an equal number of protein-coding mRNAs (red bars) and for randomly selected intronic or intergenic genomic sequences with the same length and % GC of pancreas expressed lncRNAs (light gray bars).