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. 2011 Nov 3;6:108. doi: 10.1186/1746-1596-6-108

Table 2.

Correlation between FISH EGFR and immunohistochemicals markers (mEGFR, nEGFR and Cyclin D1)

EGFR FISH
Parameters Total ≤ 2,0 - 2,49 2,5 - 2,93 ≥ 2,94 p - value

mEGFR 0.001
 neg./week 49 49 0 0
 moderate 64 53 8 3
 strong 22 15 2 5
nEGFR 0.818
 neg./week 9 9 0 0
 moderate 49 42 2 5
 strong 77 66 8 3
Cyclin D1 0.876
 neg./week 8 7 1 0
 moderate 51 45 1 5
 strong 76 65 8 3

Total 135 117

CRC, colorectal carcinoma

mEGFR, membrane EGFR

nEGFR, nuclear EGFR

test - Spearman rank correlation coefficient