Table 2.
Correlation between FISH EGFR and immunohistochemicals markers (mEGFR, nEGFR and Cyclin D1)
| EGFR FISH | |||||
|---|---|---|---|---|---|
| Parameters | Total | ≤ 2,0 - 2,49 | 2,5 - 2,93 | ≥ 2,94 | p - value |
| mEGFR | 0.001 | ||||
| neg./week | 49 | 49 | 0 | 0 | |
| moderate | 64 | 53 | 8 | 3 | |
| strong | 22 | 15 | 2 | 5 | |
| nEGFR | 0.818 | ||||
| neg./week | 9 | 9 | 0 | 0 | |
| moderate | 49 | 42 | 2 | 5 | |
| strong | 77 | 66 | 8 | 3 | |
| Cyclin D1 | 0.876 | ||||
| neg./week | 8 | 7 | 1 | 0 | |
| moderate | 51 | 45 | 1 | 5 | |
| strong | 76 | 65 | 8 | 3 | |
| Total | 135 | 117 | |||
CRC, colorectal carcinoma
mEGFR, membrane EGFR
nEGFR, nuclear EGFR
test - Spearman rank correlation coefficient