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. 2011 Nov 17;7:691–695. doi: 10.2147/NDT.S26672

Table 2.

Summary of comparisons between treatment groups

Aripiprazole (n = 149) Blonanserin (n = 67) Olanzapine (n = 95) Perospirone (n = 36) Quetiapine (n = 74) Risperidone (n = 120)
Discontinuation n (%) 83 (55.7) 53 (79.1) 74 (77.9) 27 (75.0) 48 (64.9) 92 (76.7)
Time to discontinuation (day) by Kaplan–Meier analysis 543 364 370 407 402 336
Treatment comparisons by Cox’s proportional hazards regression model
Aripiprazole
 Hazard ratio (95% CI) 0.63 (0.44–0.89) 0.62 (0.45–0.85) 0.68 (0.44–1.06) 0.74 (0.51–1.05) 0.58 (0.43–0.78)
P value 0.008** 0.003** 0.086 0.092 <0.001**
Blonanserin
 Hazard ratio (95% CI) 0.98 (0.69–1.38) 1.1 (0.70–1.76) 1.16 (0.78–1.71) 0.91 (0.65–1.28)
P value 0.9 0.69 0.48 0.59
Olanzapine
 Hazard ratio (95% CI) 1.12 (0.71–1.74) 1.16 (0.80–1.67) 0.93 (0.69–1.27)
P value 0.63 0.43 0.65
Perospirone
 Hazard ratio (95% CI) 1.06 (0.66–1.71) 0.84 (0.55–1.29)
P value 0.8 0.43
Quetiapine
 Hazard ratio (95% CI) 0.80 (0.56–1.13)
P value 0.2
**

Note: P value is statistically significant.

Abbreviation: CI, confidence interval.