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. 2011 Nov 28;6(11):e27370. doi: 10.1371/journal.pone.0027370

Figure 9. Comparison of amide proton CEST intensities versus pH for free and liposome-encapsulated TmDOTA-(gly)4 −.

Figure 9

The amide proton CEST intensity for free TmDOTA-(gly)4 − sample (3 mM, no lipid, same data as that shown in Fig. 8) and liposomal-encapsulated TmDOTA-(gly)4 − (intraliposomal concentrations of 75 mM and 150 mM) were measured as a function of pH at 9.4 T and 310 K using a B1 = 7.0 µT and a presaturation time of 6 s. The number of liposomes in the later two samples was adjusted so that the total concentration of TmDOTA-(gly)4 − in each sample was 3 mM when averaged over the entire volume.