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. 2011 Nov 28;6(11):e27910. doi: 10.1371/journal.pone.0027910

Table 1. Animal and hematological measurements.

Normoxia Chronic hypoxia
Saline Sildenafil IntReox Sildenafil+IntReox
Initial body weight, g 251±2 248±5 255±9 250±5 235±6
Gain in body weight, g 98±7 −4±10* 73±21# 16±4$ 25±5#
Heart/body weight, mg·g−1 3.76±0.11 5.57±0.22* 4.28±0.21# 5.21±0.09$ 3.75±0.16#
Hematocrit 0.51±0.02 0.66±0.02* 0.65±0.01 0.68±0.01 0.62±0.01
Hemoglobin, g·l−1 158±4 200±7* 202±5 218±3 205±4
Red blood cell count, RBC·fl−1 8.65±0.36 10.45±0.43* 10.05±0.29 9.80±0.19 9.40±0.18

*, P<0.05 when comparing untreated chronic hypoxia vs. normoxia;

#, P<0.05 when comparing the various treatments vs. untreated chronic hypoxia;

$, P<0.05 when comparing the two treatments between them. All post-tests performed with the Bonferroni method.

Data are mean±SEM.

ANOVA P<0.0001 for all measurements.