Table V.
Models | Zero order | First order | Higuchi | Korsmeyer–Peppas | |||||
---|---|---|---|---|---|---|---|---|---|
Batches | R 2 | K o | R 2 | K F | R 2 | K H | n | R 2 | K KP |
I | 0.9668 | 2.44 | 0.9274 | 0.0155 | 0.8233 | 0.1178 | 1.0194 | 0.9444 | −1.7709 |
II | 0.9887 | 3.2952 | 0.9884 | 0.0246 | 0.9295 | 0.1672 | 1.4547 | 0.9659 | −1.961 |
III | 0.91 | 4.4037 | 0.9868 | 0.0638 | 0.9655 | 0.2373 | 0.8959 | 0.9765 | −1.1114 |
IV | 0.9732 | 4.3117 | 0.9224 | 0.0616 | 0.9669 | 0.2252 | 0.9533 | 0.9922 | −1.2382 |
V | 0.9949 | 4.1945 | 0.8034 | 0.0631 | 0.9472 | 0.2141 | 0.959 | 0.9982 | −1.2995 |
VI | 0.972 | 10.233 | 0.9941 | 0.0887 | 0.9712 | 0.3055 | 0.7775 | 0.9957 | −0.7675 |
VII | 0.9351 | 5.761 | 0.9546 | 0.0729 | 0.9928 | 0.2421 | 0.3635 | 0.3230 | −0.5058 |
VIII | 0.9265 | 6.1325 | 0.9717 | 0.0762 | 0.9764 | 0.2506 | 0.5095 | 0.3681 | −0.6276 |
IX | 0.9503 | 5.7614 | 0.9879 | 0.0601 | 0.9774 | 0.2319 | 0.4763 | 0.3333 | −0.6384 |
X | 0.9965 | 4.4635 | 0.9888 | 0.0312 | 0.902 | 0.1602 | 0.0848 | 0.0066 | −0.5824 |
n drug release exponents, K KP Korsmeyer–Peppas release constant, R 2 correlation coefficient, K 0 zero-order release rate constants, K F first-order release rate constant of different models