Table III.
Storage time (days) | Average size (nm) | Zeta potential (mV) | EE of LT-NLC (%) | ||||
---|---|---|---|---|---|---|---|
LT-NLC (4°C) | LT-NLC (25°C) | LT-NLC-apo (4°C) | LT-NLC (4°C) | LT-NLC (25°C) | LT-NLC-apo (4°C) | ||
1 | 14.6 ± 1.2 | 13.8 ± 3.2 | 11.5 ± 1.2 | −29.3 ± 0.2 | −30.4 ± 0.8 | −18.7 ± 0.5 | 96.2 ± 1.3 |
7 | 14.9 ± 1.3 | 14.5 ± 2.8 | 36.3 ± 5.7a | −30 ± 1.2 | −29.5 ± 1.0 | −12.3 ± 2.2a | 95.4 ± 1.1 |
14 | 15.4 ± 1.0 | 17.3 ± 1.9 | 76.3 ± 13a | −28.7 ± 1.1 | −27 ± 0.5 | −10.5 ± 3.8a | 93.2 ± 1.8 |
21 | 15.2 ± 1.8 | 17.8 ± 1.7 | 255.8 ± 13a | −26.3 ± 1.9 | −25.5 ± 0.6 | −5.7 ± 1.1a | 93.0 ± 0.9 |
30 | 17.3 ± 1.6 | 18.4 ± 3.6 | – | −26.8 ± 1.7 | −25 ± 1.3 | – | 91.5 ± 0.7a |
EE Entrapment efficiency
aSignificant difference with the first day (p < 0.05)