Table 1.
Demographic and clinical characteristics of participants
| ALS | Controls | Statistic | |
|---|---|---|---|
| Age (years) | 52.6 (11.6) | 52.4 (7.2) | Mann-Whitney U = 52.5, Z = −0.239, p = 0.811 |
| Gender | 9 M: 5F | 6 M: 2F | Fisher’s exact test p = 1.0 |
| NART-estimated IQ | 118.0 (12.6) | 124.6 (2.7) | Mann-Whitney, U = 38.0, |
| Z = −1.023, p = 0.306 | |||
| HADS anxiety (max 21) | 7.1 (5.1) | 5.8 (2.3) | Mann-Whitney U = 47.0, |
| Z = 0.620, p = 0.536 | |||
| HADS depression (max 21) | 4.7 (3.1) | 2.5 (2.9) | Mann-Whitney U = 31.5, |
| Z = −1.685, p = 0.092 | |||
| HADS depression (modified)* (max 18) | 2.7 (2.7) | 1.8 (2.0) | Mann-Whitney U = 43.0, |
| Z = −0.909, p = 0.363 | |||
| ALSSS | N/A | N/A | |
| Bulbar (max 20) | 16.5 (4.2) Range 8–20 | ||
| Spinal (max 20) | 14.9 (3.9) Range 8–19 | ||
| Total (max 40) | 32.1 (4.9) Range 23–39 | ||
All values mean (SD)
NART National Adult Reading Test, HADS Hospital Anxiety and Depression Scale, ALSSS ALS Severity Scale
* Item “I feel as if I am slowed down” removed