Table 3.
Regions of significant difference (at p = 0.001) in activation for the Stroop effect (i.e. Stroop minus control condition) between ALS patients and healthy controls
| Cerebral region | Brodmann area(s) | Side | Coordinates of centroid point | Area (voxels) | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| ALS > CON | ||||||
| Hippocampus | – | L | −29 | −9 | −20 | 13 |
| L | −39 | −19 | −16 | 124 | ||
| Inferior temporal gyrus | 20, 37 | L | −51 | −14 | −20 | 17 |
| L | −60 | −49 | −12 | 7 | ||
| Parahippocampal gyrus | 19, 28, 36 | L | −34 | −26 | −20 | 30 |
| L | −40 | −43 | −8 | 26 | ||
| L | −38 | −44 | −4 | 4 | ||
| Fusiform gyrus | 18, 37 | L | −43 | −52 | −16 | 8 |
| L | −8 | −85 | −16 | 117 | ||
| L | −27 | −96 | −16 | 20 | ||
| Middle temporal gyrus | 20, 21, 39 | L | −49 | −28 | −12 | 98 |
| L | −55 | −33 | −8 | 110 | ||
| L | −51 | −21 | −4 | 7 | ||
| L | −58 | −30 | −4 | 13 | ||
| L | −53 | −47 | 8 | 20 | ||
| L | −40 | −67 | 20 | 71 | ||
| Lingual gyrus | 18 | L | −16 | −84 | −8 | 116 |
| L | −11 | −74 | −8 | 14 | ||
| L | −14 | −89 | −8 | 56 | ||
| Superior temporal gyrus | 21, 22, 42 | L | −51 | −20 | 1 | 10 |
| L | −51 | −20 | 4 | 10 | ||
| L | −56 | −44 | 12 | 19 | ||
| L | −47 | −53 | 12 | 25 | ||
| L | −48 | −47 | 16 | 219 | ||
| L | −49 | −36 | 20 | 124 | ||
| Cingulate gyrus | 24, 32 | L | −3 | 35 | 12 | 6 |
| L | −12 | 42 | 16 | 4 | ||
| L | −12 | 34 | 20 | 15 | ||
| L | −22 | 24 | 20 | 15 | ||
| L | −9 | 36 | 24 | 24 | ||
| L | −23 | 23 | 24 | 4 | ||
| L | −8 | 11 | 28 | 13 | ||
| L | −10 | 26 | 32 | 117 | ||
| 24, 32 | R | 1 | 34 | 16 | 5 | |
| R | 2 | 35 | 20 | 4 | ||
| Insula | – | L | −35 | 24 | 12 | 37 |
| Trans temporal gyrus | 41 | L | −50 | −19 | 12 | 13 |
| Middle occipital gyrus | 19 | L | −45 | −71 | 12 | 8 |
| Caudate nucleus | – | L | −25 | 26 | 16 | 109 |
| Medial frontal gyrus | 9 | R | 3 | 38 | 24 | 3 |
| R | 3 | 38 | 28 | 4 | ||
| 9, 32 | L | −9 | 35 | 28 | 33 | |
| L | −10 | 25 | 35 | 111 | ||
| Postcentral gyrus | 2 | L | −57 | −16 | 24 | 3 |
| Inferior parietal | 39, 40 | L | −48 | −43 | 24 | 56 |
| L | −48 | −62 | 24 | 7 | ||
| L | −41 | −40 | 40 | 73 | ||
| L | −49 | −36 | 45 | 26 | ||
| L | −35 | −44 | 45 | 19 | ||
| Superior occipital gyrus | 19 | L | −36 | −73 | 24 | 60 |
| L | −37 | −73 | 28 | 59 | ||
| L | −38 | −72 | 32 | 22 | ||
| Supramarginal gyrus | 40 | L | −53 | −38 | 28 | 23 |
| L | −38 | −46 | 28 | 13 | ||
| L | −55 | −39 | 32 | 3 | ||
| L | −35 | −43 | 32 | 14 | ||
| L | −38 | −41 | 35 | 63 | ||