TABLE 2.
P21 | P60 | |||
---|---|---|---|---|
SFR | IMS | SFR | IMS | |
H4 | 0.92 ± 0.03 | 0.80 ± 0.06 | 0.78 ± 0.09 | 0.83 ± 0.05 |
H3 | 1.50 ± 0.11 | 1.74 ± 0.11 | 0.90 ± 0.13 | 0.83 ± 0.06 |
acH3K9 | 0.56 ± 0.06 | 0.67 ± 0.02 | 0.79 ± 0.02 | 0.76 ± 0.02 |
H3me2 | 0.88 ± 0.03 | 0.89 ± 0.03 | 0.75 ± 0.02 | 0.88 ± 0.01* |
H3me3 | 1.57 ± 0.09 | 1.59 ± 0.10 | 1.11 ± 0.03 | 1.19 ± 0.05 |
Data are mean ± sem of optical densities on Western blots (n=6 per group) that were normalized to GAPDH optical densities and compared by two-tailed Student’s t test.
p<0.002 compared to SFR P60 mice.