. Author manuscript; available in PMC: 2013 Jan 1.

Published in final edited form as: Neurobiol Dis. 2011 Sep 21;45(1):488–498. doi: 10.1016/j.nbd.2011.09.005

TABLE 4.

Expression of total and post-translationally modified histone H3 and H4 proteins in the forebrain neocortex of Balb/c mice treated with fluoxetine during adolescence^a.

	IMS	IMS-fluoxetine
H4	0.62 ± 0.05	0.97 ± 0.05^**
acH4K5	0.92 ± 0.01	0.94 ± 0.02
acH4K8	1.10 ± 0.02	1.51 ± 0.06^*
acH4K12	0.50 ± 0.11	1.16 ± 0.04^***
acH4K16	0.96 ± 0.03	1.04 ± 0.04
H3	1.16 ± 0.01	1.31 ± 0.03^**
acH3K9	0.78 ± 0.03	1.21 ± 0.02^***
H3me2	1.00 ± 0.08	0.93 ± 0.03
H3me3	0.61 ± 0.03	0.94 ± 0.07^*

Data are mean ± sem of optical densities on Western blots (n=5 per group) that were normalized to GAPDH optical densities and compared by two-tailed Student’s t test.

p<0.02;

^**

p<0.001;

^***

p<0.0007.