. Author manuscript; available in PMC: 2013 Jan 1.

Published in final edited form as: Neurobiol Dis. 2011 Sep 21;45(1):488–498. doi: 10.1016/j.nbd.2011.09.005

TABLE 5.

Expression of total and post-translationally modified histone H3 and H4 proteins in the forebrain neocortex of SFR Balb/c mice treated with fluoxetine alone or in combination with SAHA^a.

	SFR-fluox	SFR-SAHA-fluox
H4	1.10 ± 0.04	1.44 ± 0.11^*
acH4K5	0.45 ± 0.06	0.87 ± 0.06^***
acH4K8	0.86 ± 0.06	1.06 ± 0.08
acH4K12	0.80 ± 0.03	1.45 ± 0.15^**
acH4K16	0.70 ± 0.06	0.71 ± 0.09
H3	0.96 ± 0.01	0.97 ± 0.01
acH3K9	0.86 ± 0.03	1.15 ± 0.18
H3me2	1.08 ± 0.04	1.07 ± 0.03
H3me3	1.12 ± 0.02	1.33 ± 0.03^***

Data are mean ± sem of optical densities on Western blots (n=5 per group) that were normalized to GAPDH optical densities and compared by two-tailed Student’s t test.

p<0.03

^**

p<0.008

^***

p<0.002.