Table 2. Summary of experimental findings.
| Drug Treatment and timing1 | Relative rate of Extinction2 [Sub-groups combined for acute DCS treatments] | Behavioral Treatments and Tests1 | |||
|---|---|---|---|---|---|
| CS-Only Extinction (CSO) | Explicitly Unpaired Extinction (EU) | ||||
| Relative rate of Extinction2 | SR test3 | Relative rate of Extinction2 | SR Test3 | ||
| Controls | +4 | +5 | SR7 | +++5 | No SR7 |
| Chronic DCS | +4 | +5 | SR7 | +++5 | SR7 |
| Acute DCS (static: 2–5%) | +++4 | ++6 | SR8 | +++6 | No SR8 |
| Acute DCS (early dynamic: 8–16%) | +6 | SR8 | +++6 | No SR8 | |
| Acute DCS (late dynamic: 20–40%) | +6 | No SR8 | +++6 | SR8 | |
1
See Table 1 for group nomenclature and procedures
2
Days to achieve asymptotic CTA extinction. Rates are relative to other groups in the same column. + = Slow rate of extinction; ++ = Medium rate of extinction; +++ = Fast rate of extinction.
3
Comparison of saccharin drunk at asymptotic CTA extinction vs. saccharin drunk at the spontaneous recovery (SR) test 30 days later. SR indicates a suppression of SAC drinking relative to the amount consumed at the end of CTA extinction.
4
See Figure 3
5
See Figure 2A
6
See Figure 4
7
See Figure 5
8
See Figure 6