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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Clin Exp Pharmacol Physiol. 2011 Dec;38(12):796–803. doi: 10.1111/j.1440-1681.2011.05609.x

Figure 3.

Figure 3

Hypoxia decreased Vmax for L-arg uptake. A) L-arg uptake determined in hPMVEC incubated with varying amounts of L-arg during normoxia (black circles) and hypoxia (grey circles). L-arg uptake by hPMVEC is a saturable process which follows Michaelis-Menton kinetics, and hypoxia decreased L-arg uptake. B) Hypoxia had no effect on the Km of L-arg uptake by hPMVEC. C) Hypoxia decreased the Vmax of L-arg uptake by hPMVEC. * hypoxia different from normoxia, p<0.05.