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. 2011 May 1;5(3):269–279. doi: 10.4161/chan.5.3.15827

Figure 1.

Figure 1

Kir4.1 is regulated by external K+. Representative I–V relationships for switches from 1 K+ to 10 K+ (A) and 10 K+ to 1 K+ (B). Time points refer to (C and D) for (A and B) respectively. (C and D) Time course of measurements from oocytes preincubated in 1 mM (C) or 10 mM (D) K+ for 1 h prior to the start of the experiment. The bath solution was switched to 10 mM (C) or 1 mM (D) K+ after 5 min and then returned to the original solution after 45 min. The currents measured at 60 mV were normalized to the value at 5 min. Control oocytes were kept in the original solution for the duration of the recording period. Boxed in values are 2.62 ± 0.33 (n = 6) vs. 0.86 ± 0.10 (n = 3) for the control (p < 0.01) in (C) and 0.66 ± 0.06 (n = 7) vs. 1.27 ± 0.10 (n = 3) for the control (p < 0.001) in (D).