Table 2.

Total estimated vaccine volume (doses in million) in five years period of dengue vaccine introduction by different vaccination schedules and options

	Option 1	Option 2	Option 3	Option 4
	Only EPI (1–2 years)	EPI (1–2 yrs) + Age 1–14 yrs Cohort	EPI (1–2 yrs) + Age 1–39 year cohort	EPI (1–2 yrs) + All ages (>1 yrs)
All country
Single dose schedule	17.8–21.3	54.8–65.6	128.6–154.1	186.6–228.0
Two dose schedule	34.9–41.9	115.0–137.8	250.8–300.6	346.9–415.7
Three dose schedule	52.6–62.9	194.3–202.6	354.8–425.1	493.2–590.9
Selected Regions*
Single dose schedule		49.5–59.3	108.4–133.3	157.7–192.4
Two dose schedule		103.7–124.2	212.1–254.1	301.4–361.1
Three dose schedule		152.5–182.7	300.9–360.6	421.0–504.5

Note: Ranges are for 10% and 25% vaccine wastage assumptions. Option 1, EPI only; Option 2, EPI⁺ 1–14 yrs cohort mass vaccination; Option 3, EPI + 1–39 yrs mass vaccination; Option 4, EPI⁺ >1 yrs all age groups. EPI, Country 1–2 age cohort for 5 years routine vaccination; Mass vaccination, one-time during 5 years.