Table 2.
p68 and p72 frequency analysis of non-overlapping hits (all over 30% and selected below 30%).
| p68 selected genes with no p72 overlap | |||
|---|---|---|---|
| Gene | % Overlap | Function | Gene Name |
| FXR1 | 42% | RNA-binding/Unknown | fragile X mental retardation, autosomal homolog 1 |
| HNRPK | 37% | Transcription/Translation/Signaling | heterogeneous nuclear ribonucleoprotein K |
| NAP1L1 | 32% | Transcription | nucleosome assembly protein 1-like 1 |
| JMJD1C | 32% | Transcription | jumonji domain containing protein 1C (Thyroid receptor interacting protein 8) |
| SFRS11 | 32% | Splicing | splicing factor, arginine/serine-rich 11 |
| MAPRE1 | 37% | Cytoskeleton | microtubule-associated protein, RP/EB family, member 1 |
| ACTG2 | 32% | Cytoskeleton | actin, gamma 2, smooth muscle, enteric |
| PTPN11 | 32% | Signal Transduction | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) |
| JAK1 | 32% | Signal Transduction | janus kinase 1 (a protein tyrosine kinase) |
| ARF3 | 32% | Vesicular Trafficking | ADP-ribosylation factor 3 |
| ANXA7 | 32% | ER-calcium mobilization | annexin A7 (Annexin VII) (Synexin) |
| COX7A2L | 32% | Metabolism | cytochrome c oxidase subunit VIIa polypeptide 2 like |
| C6orf55 | 32% | Anti-metastatic protein | protein C6orf55 (Dopamine responsive protein DRG-1) (My012 protein) |
| LAPTM4A | 32% | compartmentalization of amphipathic solutes | lysosomal-associated protein transmembrane 4 alpha |
| ZNF9 | 32% | ? | zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) |
| TDE1 | 32% | ? | tumor differentially expressed 1 |
| SYPL | 32% | ? | synaptophysin-like 1 |
| NUCKS | 32% | ? | nuclear, casein kinase and cyclin-dependant kinase substrate |
| ELK3 | 26% | Transcription | ELK3, ETS-domain protein (SRF accessory protein 2) |
| THRAP1 | 21% | Transcription | thyroid hormone receptor associated protein 1 |
| RBBP4 | 21% | Transcription | retinoblastoma binding protein 4 (chromatin assembly factor/CAF-1 p48 subunit) |
| ERBP | 21% | Transcription | estrogen receptor binding protein |
| RARA | 16% | Transcription | retinoic acid receptor, alpha |
| HDAC2 | 16% | Transcription | histone deacetylase 2 |
| SNRPB | 26% | Splicing | small nuclear ribonucleoprotein polypeptides B and B1 |
| TAPBP | 26% | ER chaperone/Protein folding | TAP binding protein (tapasin) |
| CALR | 21% | ER chaperone/Protein folding | calreticulin |
| CANX | 16% | ER Chaperone/Protein folding | calnexin |
| RAB1A | 26% | ER-golgi Transport | RAB1A, member RAS oncogene family |
| RAB11B | 21% | Membrane recycling | RAB11B, member RAS oncogene family |
| UCHL1 | 21% | Ubiquitin | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| PSMA2 | 21% | Proteolysis | proteasome (prosome, macropain) subunit, alpha type, 2 |
| PRKWNK1 | 21% | Proteolysis | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 |
| SUMO2 | 16% | SUMO pathway | small ubiquitin-like modifier, 2 |
| CDC42 | 21% | Cell-cycle | cell division cycle 42 (GTP binding protein, 25kDa) |
| CDC40 | 21% | Cell-cycle | cell division cycle 40 homolog (yeast) [pre-mRNA splicing factor 17] |
| CDC10 | 26% | Cytokinesis? | septin-7 (CDC10 protein homolog) |
| LITAF | 26% | p53-induced Apoptosis | lipopolysaccharide-induced TNF factor (p53-induced protein 7) |
| EIF3S10 | 26% | Translation | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170 kDa |
| p72 selected genes with no p68 overlap | |||
| Gene | % Overlap | Function | Gene Name |
| TTC3 | 32% | ? | tetratricopeptide repeat domain 3 |
| HMGN4 | 26% | Transcription | high mobility group nucleosomal binding domain 4 |
| CTBP1 | 21% | Transcription/corepressor | C-terminal binding protein 1 |
| MTA1 | 21% | Transcription/ER-alpha repressor | metastasis associated 1 |
| HDAC7A | 16% | Transcription | histone deacetylase 7A |
| NONO | 16% | Splicing/Transcription | non-POU domain containing, octamer-binding (p54nrb) |
| SFRS3 | 16% | Splicing | splicing factor, arginine/serine-rich 3 |
| MAP2K3 | 26% | Signal Transduction | mitogen-activated protein kinase kinase 3 |
| ERBB3 | 16% | Signal Transduction | receptor protein-tyrosine kinase erbB-3 |
| CSK | 16% | Signal Transduction | c-src tyrosine kinase |
| CALM2 | 16% | Signal Transduction | calmodulin 2 (phosphorylase kinase, delta) |
| RPS6 | 21% | Ribosome | 40S ribosomal protein S6 |
| RPS15A | 21% | Ribosome | 40S ribosomal protein S15a |
| MRPS6 | 26% | Mitochondrial Ribosome Protein | mitochondrial ribosomal protein S6 |
| PABPC1 | 26% | Translation | poly(A) binding protein, cytoplasmic 1 |
| EIF5 | 21% | Translation | eukaryotic translation initiation factor 5 |
| EDD | 26% | ubiquitin E3 Ligase | ubiquitin--protein ligase EDD |
| ARPC3 | 26% | Cytoskeleton | actin related protein 2/3 complex, subunit 3,21 kDa |
| WSB1 | 21% | ? | WD repeat and SOCS box-containing 1 |
| GARNL1 | 21% | ? | GTPase activating RANGAP domain-like 1 |
| ?-Genes with unknown function. Genes with > 30% frequency overlap are in bold. | |||
All coexpressed but non-overlapping gene products for p68 and p72 over 30% frequency are shown (and are in bold). Selected coexpressed gene products below 30% are shown and were chosen based on interest and common ontology groups.