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. 2011 Sep 1;3(5):467–478. doi: 10.4161/mabs.3.5.16089

Table 2.

Types of nanomaterials utilized in the treatment of cancer, their advantages and limitations

Class of nanomaterial Advantages Limitations Materials often utilized to construct nanomaterial
Liposomes Amphiphilic, generally biocompatible, protect drugs from degradation Large size, limited stability Phosphatidylethanolamine, phosphatidylcholine, dioleoylphosphatidylethanolamine
Polymeric Easily modified, some are biodegradable Large scale uniform production is difficult, some exhibit cytotoxicity PEG, PMLA, PGA, PLGA, block copolymers
Micelles Easily modified, generally small size, biocompatible Limited stability Polyoxyethylene, polyoxypropylene, phosphatidylethanolamine
Metals Unique optical properties, easily functionalized Not biodegradable, tend to agglomerate when exposed to physiological environment Gold, silver, platinum, copper
Non-metals Stable and resistant to environmental changes, some possess unique physical properties Generally not biodegradable, some have exhibited cytotoxic effects Silica, carbon