Table 1.
Database update numbers.
| Dataset | Oct 2006 | Oct 2008 | 2008–2006 | 2008–2006 [%] |
Filtration 2008 |
|---|---|---|---|---|---|
| GVKBIO | 1488288 | 2054151 | 565863 | 38% | -8% |
| GVKBIO Journals | 542858 | 658198 | 115340 | 21% | -8% |
| GVKBIO patents | 1034548 | 1484218 | 449670 | 43% | -7% |
| GVKBIO DD | 1933 | 3675 | 1742 | 90% | -4% |
| GVKBIO CCD | n/a | 8864 | n/a | n/a | -1% |
| GVKBIO BACE1 | n/a | 5228 | n/a | n/a | -11% |
| GVKBIO BACE1 journals | n/a | 389 | n/a | n/a | -6% |
| GVKBIO BACE1 patents | n/a | 4901 | n/a | n/a | -11% |
| WOMBAT | 128120 | 180856 | 52736 | 41% | -18% |
| PubChem | 7268193 | 14965539 | 7697346 | 106% | -23% |
| PubChem Prous | 3318 | 4652 | 1334 | 40% | -2% |
| PubChem PDB | 5626 | 5706 | n/a | n/a | -8% |
| PubChem actives | 35671 | 7472 | n/a | n/a | -3% |
| PubChem pharmacol | 6070 | 5311 | n/a | n/a | -63% |
| PubChem MLSMR | n/a | 233284 | n/a | n/a | -1% |
| PubChem BindingDB | n/a | 24203 | n/a | n/a | -4% |
| PubChem ChEBI | n/a | 7428 | n/a | n/a | -31% |
| DrugBank | 3723 | 4545 | 822 | 22% | -7% |
| DrugBank approved | 1018 | 1341 | 323 | 32% | -3% |
| DrugBank experimental | 1737 | 2999 | 1262 | 73% | -6% |
| DNP | 131831 | 144383 | 12552 | 10% | -26% |
| MDDR | 159867 | 176600 | 16733 | 10% | -4% |
| MDDR launched | 1118 | 1435 | 317 | 28% | -5% |
This shows reductions in the compound figures after filtration in this work (2008). For those data sources that were also included in our previous publication the changes (2006 – 2008) are shown in absolute numbers and as a percentage. The reasons for the decrease in two of these are explained in the methods section. New sources that are not applicable to 2006/2008 changes are labelled n/a.