Figure 7.

Number of essential gene pairs predicted using iNJ661m and iNJ661v. Flux balance analysis of iNJ661m under in vivo conditions predicted 78 essential gene pairs, whereas iNJ661v predicted 166 essential gene pairs. There were 35 gene pairs predicted to be essential by both network descriptions; 131 gene pairs were only predicted to be essential using iNJ661v, whereas 43 gene pairs were only predicted to be essential using iNJ661 m. Most of the jointly predicted gene pairs were involved in amino acid and nucleotide metabolism.