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. 2011 Nov 29;2:86. doi: 10.3389/fphys.2011.00086

Table 1.

Conventional heart rate variability measurements.

Variable Units Definition
TIME DOMAIN MEASURES
a. Statistical
SDNN ms SD of all normal R–R intervals
SDANN ms SD of the average normal R–R intervals calculated over short time periods (usually 5 min) for the entire recording period (usually 24 h)
RMSSD ms The square root of the mean squared differences between adjacent normal R–R intervals
SDNN index ms Mean of the SD of the normal R–R intervals calculated over short periods time (usually 5 min) for the entire recording period (usually 24 h)
NN50 The number of pairs of adjacent normal R–R intervals that differ by more than 50 ms
pNN50 % NN50 divided by the total number of normal R–R intervals × 100
b. Geometrical
HRV triangular index Number of normal R–R intervals divided by the height of the histogram of all the normal R–R intervals measured on discrete scale with bins of 1/128 s (7.8125 ms)
TINN ms Baseline width of the minimum square difference of triangular interpolation of the highest peak of the histogram of all normal R–R intervals
FREQUENCY DOMAIN MEASURES
Total ms2 Area under the entire power spectral curve (usually ≤0.40), variance of all normal R–R intervals
ULF ms2 Ultra low frequency power (≤0.003 Hz)
VLF ms2 Very low frequency power (0.003–0.0.04 Hz)
LF ms2 Low frequency power (0.04–0.15 Hz)
HF ms2 High Frequency power (usually 0.15–0.40 Hz*)
LFnu nu Normalized low frequency power (LF/LF + HF)
HFnu nu Normalized high frequency power (HF/LF + HF)
LF/HF Ratio of the low-to high frequency power

Nu, normalized units; *HF is shifted to higher ranges (0.24–1.04 Hz) in infants and exercising adults.