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. Author manuscript; available in PMC: 2012 May 15.
Published in final edited form as: Clin Cancer Res. 2011 Oct 5;17(22):7003–7014. doi: 10.1158/1078-0432.CCR-11-1870

Table 1. Molecular and Genetic results of the 30 new Adenoid Cystic Carcinomas.

Sample
Number
MYB-NFIB
(new primer)
3’RACEa FISH Q-PCR_MYB
(exon 2-3) (exon 15-16)
197-E8 MYB exon 9b- NFIB exon 11
MYB exon 9b- NFIB exon 12
N.P. + 10 1
327-B4 MYB exon15- NFIB exon 12 MYB exon 15- NFIB exon 12 + 62 0
236-A1 MYB exon 15- NFIB exon 12 MYB exon 15- NFIB exon 12
MYB exon 15- NFIB exon 11
+ 90 20
235-D4 MYB exon 9b- NFIB exon 11
MYB exon 9b- NFIB exon 12
N.P. + 161 5
290-F8 - MYB exon 15- NFIB 3’UTR + 162 1
381-C7 MYB exon 8b- NFIB exon 11 N.P. + 194 0
73-C3 MYB exon 15- NFIB exon 12
MYB exon 15- NFIB exon 11
N.P. + 266 18
394-D7 - MYB exon 15- NFIB 3’UTR + 358 0
404-D3 MYB exon 8b- NFIB exon 12 N.P. + 392 0
369-B5 MYB exon 8b- NFIB exon 12 N.P. + 760 4
133-C4 MYB exon 8b- NFIB exon 12 N.P. + 1516 33
163-D8 - N.P. 0 0
537-G8 - N.P. 0 1
124-C1 - N/A + 0 0
626-H6 - N.P. 3 1
598-D6 - N.P. 22 0
626-D1 - N.P. 25 0
319-H5 - N.P. 30 185
454-A8 - N.P. 62 1
321-C6 - N.P. 86 0
139-D5 - N.P. 93 69
391-F7 - N/A 133 388
383-H8 - N/A 158 80
161-B4 - N/A 226 150
610-H4 - N/A + 271 160
603-D6 - N.P. 326 171
627-C2 - N/A + 342 180
392-B2 - N/A + 388 113
288-F7 - MYB exon 13- MYB intron 13-
EFR3A intron 22 (Chr8q24.22)
+ 416 6
78-C8 - N/A + 691 237
Molecular genetic results of the subset of ACC with alterations from previous study.
Sample
Number
MYB-NFIB
(new primer)
3’RACEa FISH Q-PCR_MYB
(exon 2-3) (exon 15-16)
405-B2 - MYB exon 15- PDCDILG2
(chr 9; intron 3, inversion)
+ 106 0
b485-F7 - N/A + 231 421
233-C2 - N/A + 177 188
526-B5 - N/A + 368 213
471-F2 - N/A + 105 288
484-H3 - N/A + 105 213
594-D3 - N/A + 128 34
542-A1 - MYB exon 14- NFIB 3’UTR + 881 29
502-A5 - N/A + 606 384
185-G8 MYB exon 11- NFIB exon 12 MYB exon 11- NFIB exon 12 + 1264 635
335-C6 MYB exon 8b- NFIB exon 12 MYB exon 8b- NFIB exon 12 + 1229 5
191-D6 MYB exon11- NFIB exon 12 MYB exon 11- NFIB exon 12 + 488 62
318-H3 - MYB exon/intron 11- NFIB
3’UTR
+ 0 0
391-D6 MYB exon 12- NFIB exon 11 MYB exon 15- NFIB exon 11 + 23 0
436-E2 MYB exon 8a- NFIB exon 12
MYB exon 8a- NFIB exon 11
MYB exon 8a- NFIB exon 12 + 1217 5
436-H3 - N/A + 229 476
570-H7 MYB exon 8a- NFIB exon 12 MYB exon 8a- NFIB exon 12 + 446 0

Note:

a

N.P., not performed; N/A, No-Abnormality (MYB gene is intact at 3’region). (−), negative; (+), positive.

Note:

a

N/A, No-Abnormality (MYB gene is intact at 3’region). (−), negative; (+), positive.

b

485-F7 sample had a NFIB-AIG1 gene fusion