Table 2.

Multifactorial (Cox) regression analysis of factors affecting 12-year overall survival of ACC patients

Variable	No.	Univariate analysis HR (95% Cl)	pa	Multivariate analysisc HR (95% Cl)	pa
MYB-NFIB transcript
negative	63	1.00	0.12	N/A	N/A
positive	39	1.602 (0.892-2.844)
FISH
negative	48	1.00	0.07	N/A	N/A
positive	54	1.734 (0.947-3.173)
MYB expression (exon2-3) b
Low	76	1.00	0.005	1.00	0.014
High	26	1.003 (1.001-1.005)		1.003 (1.001-1.005)
Age
<60	67	1.00	0.008	1.00	0.008
≥60	35	1.057 (1.016-1.100)		1.055 (1.014-1.097)
Gender
Female	41	1.00	0.64	N/A	N/A
Male	61	1.154 (0.639-2.087)
Size
<4cm	63	1.00	0.94	N/A	N/A
≥4cm	35	0.987 (0.723-1.349)
Pattern
Not Solid	60	1.00	<0.001	1.00	<0.001
Solid	41	3.706 (2.027-6.777)		3.596 (1.963-6.589)
PNI
No	7	1.00	0.58	N/A	N/A
Yes	78	1.499 (0.361-6.229)
Stage c
I-II	20	1.00	0.14	N/A	N/A
III-IV	35	1.919 (2.027-6.777)
Metastasis
No	50	1.00	0.97	N/A	N/A
Yes	52	1.012 (0.564-1.817)

^aWald p-value.

^b470 was defined as a cut-off value for MYB expression (exon2-3).

^c55 patients are available for the staging analysis.

Overall Model, p<0.00001. N/A = not applicable

PNI: Perineural invasion